Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy
| Data(s) |
09/07/2004
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| Resumo |
Transcriptome analysis using microarray technology represents a powerful unbiased approach for delineating pathogenic mechanisms in disease. Here molecular mechanisms of renal tubulointerstitial fibrosis (TIF) were probed by monitoring changes in the renal transcriptome in a glomerular disease-dependent model of TIF ( adriamycin nephropathy) using Affymetrix (mu74av2) microarray coupled with sequential primary biological function-focused and secondary |
| Identificador |
http://dx.doi.org/10.1074/jbc.M313408200 http://www.scopus.com/inward/record.url?scp=3142676670&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Sadlier , D M , Connolly , S B , Kieran , N E , Roxburgh , S , Brazil , D , Kairaitis , L , Wang , Y , Harris , D C H , Doran , P & Brady , H R 2004 , ' Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy ' Journal of biological chemistry , vol 279 , no. 28 , pp. 29670-29680 . DOI: 10.1074/jbc.M313408200 |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1300/1303 #Biochemistry |
| Tipo |
article |
