Relative activity of triclabendazole metabolites against the liver fluke, Fasciola hepatica


Autoria(s): Halferty, Liam; Brennan, Gerard; Trudgett, Alan; Hoey, Elizabeth; Fairweather, Ian
Data(s)

05/02/2009

Resumo

A study has been carried Out to determine the relative activity Of triclabendazole (TCBZ) and its sulphoxide (TCBZ(center dot)SO) and sulphone (TCBZ(center dot)SO(2)) metabolites against the adult stage of the liver fluke, Fasciola hepatica. Flukes were incubated for 24 h in vitro in 15 mu g/ml of each of the compounds and prepared for scanning and transmission electron microscopy.

Identificador

http://pure.qub.ac.uk/portal/en/publications/relative-activity-of-triclabendazole-metabolites-against-the-liver-fluke-fasciola-hepatica(d1a34878-63c8-421c-851f-1ff2c3eaf94a).html

http://dx.doi.org/10.1016/j.vetpar.2008.10.007

http://www.scopus.com/inward/record.url?scp=58149464100&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Halferty , L , Brennan , G , Trudgett , A , Hoey , E & Fairweather , I 2009 , ' Relative activity of triclabendazole metabolites against the liver fluke, Fasciola hepatica ' Veterinary Parasitology , vol 159 , no. 2 , pp. 126-138 . DOI: 10.1016/j.vetpar.2008.10.007

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2400/2405 #Parasitology #/dk/atira/pure/subjectarea/asjc/3400 #veterinary(all)
Tipo

article