Clinical Determinants of Response to Irinotecan-Based Therapy Derived from Cell Line Models
| Data(s) |
15/10/2008
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|---|---|
| Resumo |
Purpose: In an attempt to identify genes that are involved in resistance to SN38, the active metabolite of irinotecan (also known as CPT-11), we carried out DNA microarray profiling of matched HCT116 human colon cancer parental cell lines and SN38-resistant cell lines following treatment with SN38 over time. |
| Identificador |
http://dx.doi.org/10.1158/1078-0432.CCR-08-0452 http://www.scopus.com/inward/record.url?scp=58149198582&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Allen , W , Coyle , V , Jithesh , P , Proutski , I , Stevenson , L , Fenning , C , Longley , D , Wilson , R , Gordon , M , Lenz , H J & Johnston , P 2008 , ' Clinical Determinants of Response to Irinotecan-Based Therapy Derived from Cell Line Models ' Clinical Cancer Research , vol 14 , no. 20 , pp. 6647-6655 . DOI: 10.1158/1078-0432.CCR-08-0452 |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1300/1306 #Cancer Research #/dk/atira/pure/subjectarea/asjc/2700/2730 #Oncology |
| Tipo |
article |
