One-pot multistep synthetic strategies for the production of fenpropimorph using an ionic liquid solvent
| Data(s) |
01/11/2006
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|---|---|
| Resumo |
The one-pot synthesis of the fungicide fenpropimorph has been achieved using two different synthetic strategies in an ionic liquid. The first pathway consists of a Heck coupling followed by reductive amination; the second pathway consists of an aldol condensation followed by hydrogenation/reductive amination. Homogeneous and heterogeneous palladium catalysts have been utilised in the ionic liquid to provide a catalyst/solvent system that is suitable for recycling and process optimisation. |
| Identificador |
http://dx.doi.org/10.1021/op050172m http://www.scopus.com/inward/record.url?scp=33344455013&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Forsyth , S , Gunaratne , N , Hardacre , C , McKeown , A & Rooney , D 2006 , ' One-pot multistep synthetic strategies for the production of fenpropimorph using an ionic liquid solvent ' Organic Process Research & Development , vol 10 (1) , no. 1 , pp. 94-102 . DOI: 10.1021/op050172m |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/3000/3002 #Drug Discovery #/dk/atira/pure/subjectarea/asjc/1600/1605 #Organic Chemistry |
| Tipo |
article |
