Carboxypeptidase-mediated metabolism of calcitonin gene-related peptide in human gingival crevicular fluid - a role in periodontal inflammation?


Autoria(s): Lundy, Fionnuala; Salmon, A.L.; Lamey, Philip; Shaw, Christopher; Linden, Gerard
Data(s)

2000

Resumo

Background: Metabolism by peptidases plays an important role in modulating the levels of biologically-active neuropeptides. The metabolism of the anti-inflammatory neuropeptide calcitonin gene-related peptide (GCRP), but not the pro-inflammatory neuropeptides substance P (SP) and neurokinin A (NKA) by components of the gingival crevicular fluid (GCF), could potentiate the inflammatory process in periodontitis.

Identificador

http://pure.qub.ac.uk/portal/en/publications/carboxypeptidasemediated-metabolism-of-calcitonin-generelated-peptide-in-human-gingival-crevicular-fluid--a-role-in-periodontal-inflammation(e4a15a4f-a1c7-4b91-8aca-b8f41f322d7c).html

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Lundy , F , Salmon , A L , Lamey , P , Shaw , C & Linden , G 2000 , ' Carboxypeptidase-mediated metabolism of calcitonin gene-related peptide in human gingival crevicular fluid - a role in periodontal inflammation? ' Journal of Clinical Periodontology , vol 27 , pp. 499-505 .

Tipo

article