A concise and convergent (formal) total synthesis of huperzine A


Autoria(s): Mann, John; Lucey, C.; Kelly, S.
Data(s)

01/01/2007

Resumo

The first convergent synthesis of the tricyclic skeleton of huperzine A is described and includes, as the key step, an efficient regioselective intramolecular Heck reaction of 2-(tert-butyldimethylsillyoxymethyl)-6-(2-methoxy-5-bromopyridin-6-yl)methylcyclohex-2-enol.

Identificador

http://pure.qub.ac.uk/portal/en/publications/a-concise-and-convergent-formal-total-synthesis-of-huperzine-a(5286926a-5d27-4aa9-85e0-334b7f40d83b).html

http://dx.doi.org/10.1039/b615059d

http://www.scopus.com/inward/record.url?scp=33846046387&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Mann , J , Lucey , C & Kelly , S 2007 , ' A concise and convergent (formal) total synthesis of huperzine A ' Organic and Biomolecular Chemistry , vol 5(2) , no. 2 , pp. 301-306 . DOI: 10.1039/b615059d

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1300 #Biochemistry, Genetics and Molecular Biology(all) #/dk/atira/pure/subjectarea/asjc/1600 #Chemistry(all)
Tipo

article