Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane.


Autoria(s): Davies, Jerry; Malone, John; Boyd, Derek; Stein, B.K.; Stevenson, C.; Kumar, S.; Lyle, J.; Cosby, L.; Sharma, Narain; Hunter, A.P.
Data(s)

01/05/2002

Resumo

Treatment of guanosine or 2'-deoxyguanosine with dimethyldioxirane, followed by heating in aqueous solution, generates respectively 4-amidinocarbamoyl-5-hydroxyimidazole (1) or its 2-(2,3,4-trihydroxybutyl) derivative (2).

Identificador

http://pure.qub.ac.uk/portal/en/publications/novel-oxidation-products-from-guanine-nucleosides-reacted-with-dimethyldioxirane(d2e0f0d5-3445-4561-a4a0-34f7a9264baf).html

http://dx.doi.org/10.1039/b201418c

http://www.scopus.com/inward/record.url?scp=0036087127&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Davies , J , Malone , J , Boyd , D , Stein , B K , Stevenson , C , Kumar , S , Lyle , J , Cosby , L , Sharma , N & Hunter , A P 2002 , ' Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane. ' Chemical Communications , vol 2002(13) , no. 13 , pp. 1378-1379 . DOI: 10.1039/b201418c

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1600 #Chemistry(all)
Tipo

article