Low-dose vitamin B-6 effectively lowers fasting plasma homocysteine in healthy elderly persons who are folate and riboflavin replete.
| Data(s) |
01/04/2001
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|---|---|
| Resumo |
BACKGROUND: Current data suggest that physiologic doses of vitamin B-6 have no significant homocysteine-lowering effect. It is possible that an effect of vitamin B-6 was missed in previous trials because of a much greater effect of folic acid, vitamin B-12, or both. OBJECTIVE: The aim of this study was to investigate the effect of low-dose vitamin B-6 supplementation on fasting total homocysteine (tHcy) concentrations in healthy elderly persons who were made replete with folate and riboflavin. DESIGN: Twenty-two healthy elderly persons aged 63-80 y were supplemented with a low dose of vitamin B-6 (1.6 mg/d) for 12 wk in a randomized, double-blind, placebo-controlled trial after repletion with folic acid (400 microg/d for 6 wk) and riboflavin (1.6 mg/d for 18 wk); none of the subjects had a vitamin B-12 deficiency. RESULTS: Folic acid supplementation lowered fasting tHcy by 19.6% (P |
| Formato |
application/pdf |
| Identificador |
http://pure.qub.ac.uk/ws/files/324467/McKinley%20AJCN%202001%20Low%20dose%20vitamin%20B-6.....pdf http://www.scopus.com/inward/record.url?scp=0035076561&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
McKinley , M , McNulty , H , McPartlin , J , Strain , J J , Pentieva , K , Ward , M , Weir , D G & Scott , J M 2001 , ' Low-dose vitamin B-6 effectively lowers fasting plasma homocysteine in healthy elderly persons who are folate and riboflavin replete. ' American Journal of Clinical Nutrition , vol 73 (4) , no. 4 , pp. 759-764 . |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/2700/2701 #Medicine (miscellaneous) #/dk/atira/pure/subjectarea/asjc/1100/1106 #Food Science |
| Tipo |
article |
