Integrated biomedical device for blood preparation


Autoria(s): Kersaudy-Kerhoas, Maïwenn; Kavanagh, Deirdre; Xue, Xiangdong; Patel, Mayur; Bailey, Christopher; Dhariwal, Resham; Desmulliez, Marc P.Y.
Data(s)

01/09/2008

Resumo

The separation of red blood cells from plasma flowing in microchannels is possible by bio-physical effects such as an axial migration effect and Zweifach-Fung bifurcation law. In the present study, subchannels are placed alongside a main channel to collect cells and plasma separately. The addition of a constriction in the main microchannel creates a local high shear force region, forcing the cells to migrate and concentrate towards the centre of the channel. The resulting lab-on-a-chip was manufactured using biocompatible materials. Purity efficiency was measured for mussel and human blood suspensions as different parameters including flow rate and geometries of parent and daughter channels were varied.

Formato

application/pdf

Identificador

http://gala.gre.ac.uk/1238/1/08_47.pdf

Kersaudy-Kerhoas, Maïwenn, Kavanagh, Deirdre, Xue, Xiangdong, Patel, Mayur, Bailey, Christopher, Dhariwal, Resham and Desmulliez, Marc P.Y. (2008) Integrated biomedical device for blood preparation. 2nd Electronics System-Integration Technology Conference, 2008. ESTC 2008. Institute of Electrical and Electronics Engineers, Inc., Piscataway, NJ, USA, pp. 447-452. ISBN 978-1-4244-2814-4 (Print) 978-1-4244-2813-7 (Online) (doi:10.1109/ESTC.2008.4684389 <http://doi.org/10.1109/ESTC.2008.4684389>)

Idioma(s)

en

Publicador

Institute of Electrical and Electronics Engineers, Inc.

Relação

http://gala.gre.ac.uk/1238/

http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=4684389

10.1109/ESTC.2008.4684389

Palavras-Chave #R Medicine (General) #QA Mathematics
Tipo

Book Section

PeerReviewed