In vivo visualization of abdominal malignancies with acoustic radiation force elastography.
Data(s) |
07/01/2008
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Formato |
279 - 293 |
Identificador |
http://www.ncbi.nlm.nih.gov/pubmed/18182703 S0031-9155(08)56898-9 Phys Med Biol, 2008, 53 (1), pp. 279 - 293 0031-9155 |
Relação |
Phys Med Biol 10.1088/0031-9155/53/1/020 |
Tipo |
Journal Article |
Cobertura |
England |
Resumo |
The utility of acoustic radiation force impulse (ARFI) imaging for real-time visualization of abdominal malignancies was investigated. Nine patients presenting with suspicious masses in the liver (n = 7) or kidney (n = 2) underwent combined sonography/ARFI imaging. Images were acquired of a total of 12 tumors in the nine patients. In all cases, boundary definition in ARFI images was improved or equivalent to boundary definition in B-mode images. Displacement contrast in ARFI images was superior to echo contrast in B-mode images for each tumor. The mean contrast for suspected hepatocellular carcinomas (HCCs) in B-mode images was 2.9 dB (range: 1.5-4.2) versus 7.5 dB (range: 3.1-11.9) in ARFI images, with all HCCs appearing more compliant than regional cirrhotic liver parenchyma. The mean contrast for metastases in B-mode images was 3.1 dB (range: 1.2-5.2) versus 9.3 dB (range: 5.7-13.9) in ARFI images, with all masses appearing less compliant than regional non-cirrhotic liver parenchyma. ARFI image contrast (10.4 dB) was superior to B-mode contrast (0.9 dB) for a renal mass. To our knowledge, we present the first in vivo images of abdominal malignancies in humans acquired with the ARFI method or any other technique of imaging tissue elasticity. |
Idioma(s) |
ENG |
Palavras-Chave | #Abdominal Neoplasms #Acoustics #Aged #Aged, 80 and over #Biophysical Phenomena #Biophysics #Carcinoma, Hepatocellular #Elasticity Imaging Techniques #Female #Humans #Kidney Neoplasms #Liver Neoplasms #Male #Middle Aged #Tomography, X-Ray Computed |