Human CD19 and CD40L deficiencies impair antibody selection and differentially affect somatic hypermutation.

Autoria(s): van Zelm, Menno C; Bartol, Sophinus J W; Driessen, Gertjan J; Mascart, Françoise; Reisli, Ismail; Franco, Jose L; Wolska-Kusnierz, Beata; Kanegane, Hirokazu; Boon, Louis; van Dongen, Jacques J M; van der Burg, Mirjam
Data(s)

01/01/2014
Resumo

Individuals with genetic defects in CD40 ligand (CD40L) or B-cell antigen receptor coreceptor molecules CD19 and CD81 suffer from an antibody deficiency. Still, these patients carry low levels of memory B cells and serum antibodies.

JOURNAL ARTICLE

SCOPUS: ar.j

info:eu-repo/semantics/published
Formato

1 full-text file(s): application/pdf
Identificador

uri/info:doi/10.1016/j.jaci.2013.11.015

uri/info:pii/S0091-6749(13)01778-8

uri/info:pmid/24418477

https://dipot.ulb.ac.be/dspace/bitstream/2013/155370/1/Elsevier_140223.pdf

http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/155370
Idioma(s)

other
Direitos

1 full-text file(s): info:eu-repo/semantics/restrictedAccess
Fonte

Journal of allergy and clinical immunology
Palavras-Chave #Immunologie
Tipo

info:eu-repo/semantics/article

info:ulb-repo/semantics/articlePeerReview

info:ulb-repo/semantics/openurl/article
Acesso ao item digital