Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA.
Data(s) |
01/02/2010
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Formato |
197 - 204 |
Identificador |
http://www.ncbi.nlm.nih.gov/pubmed/20113547 Emerg Infect Dis, 2010, 16 (2), pp. 197 - 204 http://hdl.handle.net/10161/6345 1080-6059 |
Relação |
Emerg Infect Dis 10.3201/eid1602.090953 Emerging Infectious Diseases |
Tipo |
Journal Article |
Cobertura |
United States |
Resumo |
We determined estimated incidence of and risk factors for community-associated Clostridium difficile infection (CA-CDI) among patients treated at 6 North Carolina hospitals. CA-CDI case-patients were defined as adults (>18 years of age) with a positive stool test result for C. difficile toxin and no hospitalization within the prior 8 weeks. CA-CDI incidence was 21 and 46 per 100,000 person-years in Veterans Affairs (VA) outpatients and Durham County populations, respectively. VA case-patients were more likely than controls to have received antimicrobial drugs (adjusted odds ratio [aOR] 17.8, 95% confidence interval [CI] 6.6-48] and to have had a recent outpatient visit (aOR 5.1, 95% CI 1.5-17.9). County case-patients were more likely than controls to have received antimicrobial drugs (aOR 9.1, 95% CI 2.9-28.9), to have gastroesophageal reflux disease (aOR 11.2, 95% CI 1.9-64.2), and to have cardiac failure (aOR 3.8, 95% CI 1.1-13.7). Risk factors for CA-CDI overlap with those for healthcare-associated infection. |
Idioma(s) |
ENG |
Palavras-Chave | #Adult #Age Distribution #Aged #Aged, 80 and over #Bacterial Proteins #Bacterial Toxins #Case-Control Studies #Clostridium Infections #Community-Acquired Infections #Dysentery #Enterotoxins #Feces #Female #Humans #Incidence #Male #Middle Aged #North Carolina #Odds Ratio #Prejudice #Risk Factors #Veterans #Young Adult |