Bacterial vaginosis as a risk factor for high-grade cervical lesions and cancer in HIV-seropositive women.
| Data(s) |
01/09/2011
|
|---|---|
| Formato |
273 - 277 |
| Identificador |
http://www.ncbi.nlm.nih.gov/pubmed/21683359 S0020-7292(11)00246-3 Int J Gynaecol Obstet, 2011, 114 (3), pp. 273 - 277 http://hdl.handle.net/10161/5915 1879-3479 |
| Idioma(s) |
ENG en_US |
| Relação |
Int J Gynaecol Obstet 10.1016/j.ijgo.2011.03.011 International Journal of Gynecology and Obstetrics |
| Palavras-Chave | #Adolescent #Adult #Aged #Cervical Intraepithelial Neoplasia #Female #HIV Seropositivity #Humans #Middle Aged #Prospective Studies #Risk Factors #Uterine Cervical Neoplasms #Vaginosis, Bacterial #Young Adult |
| Tipo |
Journal Article |
| Cobertura |
Ireland |
| Resumo |
OBJECTIVE: To assess the effect of bacterial vaginosis (BV) on the risk of high-grade squamous intraepithelial lesions (HSIL) among HIV-seropositive women. METHODS: A hospital-based prospective cohort study of HIV-seropositive women was conducted in Johannesburg, South Africa from January 2005 to September 2009. Multivariate log-binomial and Poisson regressions were used to estimate prevalence and rate ratios, respectively. RESULTS: Among 1954 HIV-seropositive women, the baseline prevalence of HSIL was 17%. BV prevalence was high (54%) and showed no association with prevalence of HSIL (adjusted prevalence ratio, 1.12; 95% confidence intervals (CI), 0.92-1.35) nor with cervical lesion progression at follow-up visit (n=503) (adjusted rate ratio: 1.00; 95% CI, 0.65-1.53). CONCLUSION: Among HIV-seropositive women, BV was not associated with an increased risk of HSIL or cervical lesion progression. |
