Genome-scale analyses of health-promoting bacteria: probiogenomics
| Contribuinte(s) |
Science Foundation Ireland Health Research Board Department of Agriculture and Food, Ireland European Commission Parmalat SpA, Italy Ministero dell’Istruzione, dell’Università e della Ricerca, Italy |
|---|---|
| Data(s) |
16/02/2010
16/02/2010
01/01/2009
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| Resumo |
The human body is colonized by an enormous population of bacteria (microbiota) that provides the host with coding capacity and metabolic activities. Among the human gut microbiota are health-promoting indigenous species (probiotic bacteria) that are commonly consumed as live dietary supplements. Recent genomics-based studies (probiogenomics) are starting to provide insights into how probiotic bacteria sense and adapt to the gastrointestinal tract environment. In this Review, we discuss the application of probiogenomics in the elucidation of the molecular basis of probiosis using the well-recognized model probiotic bacteria genera Bifidobacterium and Lactobacillus as examples. Science Foundation Ireland (CSET); Department of Agriculture and Food, Ireland; Health Research Board (FHRI award); Ministero dell’Istruzione, dell’Università e della Ricerca, Italy (Italian Award for Outstanding Young Researcher scheme "Incentivazione alla mobilità di studiosi stranieri e italiani residente all’estero" 2005-2009); European Commission (Marie Curie Reintegration Grant MERG-CT-2005-03080); Parmalat SpA, Italy Accepted Version Peer reviewed |
| Identificador |
Ventura M., O'Flaherty S., Claesson M. J., Turroni F., Klaenhammer T.R., van Sinderen D., O'Toole P.W. 2009. Genome-scale analyses of health-promoting bacteria: probiogenomics. Nature Reviews Microbiology 7, pp61-71 doi:10.1038/nrmicro2047 7 1 61 71 1740-1526 1740-1534 http://hdl.handle.net/10468/118 10.1038/nrmicro2047 Nature Reviews. Microbiology |
| Idioma(s) |
en |
| Publicador |
Nature Publishing Group |
| Direitos |
© 2009 Macmillan Publishers Limited. All rights reserved http://www.nature.com/authors/editorial_policies/license.html |
| Palavras-Chave | #Genomics #Functional genomics #Microbiota #Intestinal tract #Probiotic bacteria #Bifidobacterium -- Genomics #Lactobacillus -- Genomics |
| Tipo |
Article (peer-reviewed) |
| Formato |
application/pdf |
