Determination of dissociation constants of Strychnos alkaloids from Strychnos nux-vomica L. by capillary electrophoresis


Autoria(s): Fu, SP; Zhang, XZ; Zhang, F; Xu, Q; Xiao, HB; Liang, XM
Data(s)

01/07/2005

Resumo

An accurate capillary electrophoresis method was developed for the determination of dissociation constants of five Strychnos alkaloids from Strychnos nux-vomica L. The method relies on measuring the effective mobility of the solute as a function of the buffer pH. The mathematical relationship was strictly derived from the fundamental electrophoresis theory and the dissociation equilibrium of a weak base without any simplifications. Careful optimization of the running buffer permitted base-line resolution of the five structurally similar alkaloids.

Identificador

http://159.226.238.44/handle/321008/92367

http://www.irgrid.ac.cn/handle/1471x/184195

Idioma(s)

英语

Fonte

付绍平;张晓哲;张峰;徐青;肖红斌;梁鑫淼.Determination of dissociation constants of Strychnos alkaloids from Strychnos nux-vomica L. by capillary electrophoresis,Microchimica Acta,2005,150(3—4):305-310

Palavras-Chave #dissociation constants #Strychnos alkaloids #capillary electrophoresis
Tipo

期刊论文