Synthesis, structure and biological activities of 2-(4-methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide


Autoria(s): Liu, FQ; Qin, YQ; Li, WH; Yang, SH; Lu, LD; Yang, XJ; Wang, X; Hou, BR
Data(s)

01/05/2005

Resumo

The title compound, 2-(methoxybenzoyl)-N-phenyt-2-(1,2,4-triazol-1-yl)thioacetamide was synthesized by several reactions from 4-methoxyacetophenone, triazole and phenyl isothiocyanate. The structure was identified by elemental analysis, H-1 NMR, MS and IR. The single crystal structure of 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was determined with X-ray diffraction. The preliminary bioassays show that the title compound exhibits weak antifungal activities and plant-growth regulatory activity.

The title compound, 2-(methoxybenzoyl)-N-phenyt-2-(1,2,4-triazol-1-yl)thioacetamide was synthesized by several reactions from 4-methoxyacetophenone, triazole and phenyl isothiocyanate. The structure was identified by elemental analysis, H-1 NMR, MS and IR. The single crystal structure of 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was determined with X-ray diffraction. The preliminary bioassays show that the title compound exhibits weak antifungal activities and plant-growth regulatory activity.

Identificador

http://ir.qdio.ac.cn/handle/337002/2297

http://www.irgrid.ac.cn/handle/1471x/168269

Idioma(s)

英语

Fonte

Liu, FQ; Qin, YQ; Li, WH; Yang, SH; Lu, LD; Yang, XJ; Wang, X; Hou, BR.Synthesis, structure and biological activities of 2-(4-methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide,CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2005,21(3):280-283

Palavras-Chave #Chemistry, Multidisciplinary #1 #thioamide #crystal structure #biological activities #2 #4-trizole
Tipo

期刊论文