Studies on the interaction of rare earth ions with BSA


Autoria(s): Li XJ; Zhang SR; Zhang SG; Pei FK
Data(s)

1999

Resumo

Studies on the bounding character of rare earth ions with borine serum albumin(BSA) are significant for understanding the state of rare earth ions in body and their effects on the structure and function of protein. The fluorescence spectrum and pH potentiometry showed consistent results of apparent complexion constant of Tb-2 . BSA. The equilibrium dialysis showed that there are two specific binding sites and more than six non-specific binding sites of RE ions onto BSA molecule with the conditional stable constants lg K-1 = 5. 157 and lgK(2) = 3. 435. Na-23 NMR studies revealed that the BSA peptide chain bound to RE ions was expanded and the mobility of its molecular backbone was increased.

Identificador

http://202.98.16.49/handle/322003/21999

http://www.irgrid.ac.cn/handle/1471x/155734

Idioma(s)

中文

Fonte

Li XJ;Zhang SR;Zhang SG;Pei FK.Studies on the interaction of rare earth ions with BSA,CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,1999,20(1):127-131

Tipo

期刊论文