Binuclear lanthanide complexes as catalysts for the hydrolysis of double-stranded DNA
| Data(s) |
1999
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|---|---|
| Resumo |
The efficient cleavage of plasmid DNA ( pCAT) by binuclear lanthanide complexes was investigated. At 37 degrees C and neutral pH, both Ho23+L and Er23+L promoted 100% conversion of supercoiled plasmid to the nicked circular form and linear form in 1 h. The corresponding saturation kinetics curve of cleavage of pCAT plasmid by binuclear lanthanide complexes showed the expected increase with catalyst concentration. (C) 1999 Elsevier Science S.A. All rights reserved. |
| Identificador | |
| Idioma(s) |
英语 |
| Fonte |
Zhu B;Zhao DQ;Ni JZ;Zeng QH;Huang BQ;Wang ZL.Binuclear lanthanide complexes as catalysts for the hydrolysis of double-stranded DNA,INORGANIC CHEMISTRY COMMUNICATIONS,1999,2(8):351-353 |
| Palavras-Chave | #DEOXYRIBONUCLEOSIDE 3' #EFFICIENT #CLEAVAGE #CERIUM(IV) #PEROXIDE #DIESTER #OXYGEN #IONS #RNA #5'-CYCLIC PHOSPHATE |
| Tipo |
期刊论文 |
