Studies of Gd-diethylenetriamine pentaacetic acid in boving serum albumin solution by nuclear magnetic resonance spectroscopy
Data(s) |
2000
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Resumo |
In this paper, the water relaxation enhancement behavior of Gd-diethylenetriamine pentaacetic acid(DTPA) in water and in aqueous solution of bovine serum albumine(BSA) has been studied. The T-1 relaxivity of Gd-DTPA in BSA solution is higher than that in aqueous solution. The results indicate that Gd-DTPA can integrate non-covalently with BSA mainly in forms of (Gd-DTPA) . BSA, (Gd-DTPA)(2) . BSA, for which the apparent equilibrium constant is 0.026 mmol(-1).L,0.0018 mmol(-2).L-2 respectively. This method would be used to study the interactivities between protein and contrast agent. |
Identificador | |
Idioma(s) |
中文 |
Fonte |
Li XJ;Feng JH;Li XY;Wu YJ;Pei FK.Studies of Gd-diethylenetriamine pentaacetic acid in boving serum albumin solution by nuclear magnetic resonance spectroscopy,CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2000,28(3):269-272 |
Palavras-Chave | #PROTON RELAXATION #GADOLINIUM(III) #COMPLEXES #DTPA #AGENTS |
Tipo |
期刊论文 |