Analysis of norditerpenoid alkalods in processing Radix Aconiti Lateralis preparata with Radix Glycyrrhizae Preparata by electrospray ionization tandem mass spectrometry
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2007
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Resumo |
Norditerpenoid alkaloids in the processing of Radix aconiti lateralis preparata with Radix glycyrrhizae preparata was studied by electrospray ionization tandem mass spectrometry. A method of ESI-MS couple with internal standard was applied for semi quantitative analysis of norditerpenoid alkaloids before and after processing. The combined-decoction-to single-decoction-ratios of the relative abundance of toxic hypaconitine, mesaconitine and aconitine were 5. 67%, 4. 05% and 4. 88%, respectively. The chemical changes of processing can been comprehensive observed by ESI-MS/MS analysis. The scientific basis of reducing the toxicity of Radix aconiti lateralis preparata with Radix glycyrrhizae preparata was enlightened by compareing with the single-decotion, the combined-decoction and residue for the compatibility of Radix aconiti lateralis preparata and Radix glycyrrhizae preparata. |
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中文 |
Fonte |
Yue H;Pi ZF;Zhao YF;Song FR;Liu ZQ;Liu SY.Analysis of norditerpenoid alkalods in processing Radix Aconiti Lateralis preparata with Radix Glycyrrhizae Preparata by electrospray ionization tandem mass spectrometry,CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2007 ,35(7):959-963 |
Palavras-Chave | #MESACONITINE |
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期刊论文 |