Vilsmeier Reaction of Enaminones: Efficient Synthesis of Halogenated Pyridin-2(1H)-ones
| Data(s) |
2008
|
|---|---|
| Resumo |
A facile and efficient one-pot synthesis of halogenated pyridin-2(1H)-ones from a series of readily available enaminones under Vilsmeier conditions is described, and a mechanism involving sequential halogenation, formylation, and intramolecular nucleophilic cyclization is proposed. |
| Identificador | |
| Idioma(s) |
英语 |
| Fonte |
Zhang R;Zhang DY;Guo YL;Zhou GY;Jiang ZJ;Dong DW.Vilsmeier Reaction of Enaminones: Efficient Synthesis of Halogenated Pyridin-2(1H)-ones,JOURNAL OF ORGANIC CHEMISTRY,2008,73(23):9504-9507 |
| Palavras-Chave | #HIGHLY SUBSTITUTED PYRIDIN-2(1H)-ONES #ONE-POT SYNTHESIS #FACILE SYNTHESIS #HAACK REACTIONS #ASYMMETRIC HYDROGENATION #ACRYLATE DERIVATIVES #CARBONYL-COMPOUNDS #ACID-DERIVATIVES #PYRIDINE RINGS #INHIBITORS |
| Tipo |
期刊论文 |
