Preparation and Characterization of Interpenetration Polymer Network Films Based on Poly(vinyl alcohol) and Poly(acrylic acid) for Drug Delivery


Autoria(s): Yue YM; Xu K; Liu XG; Chen Q; Sheng X; Wang PX
Data(s)

2008

Resumo

A series of full interpenetrating polymer network (full-IPN) films of poly(acrylic acid) (PAA)/poly (vinyl alcohol) (PVA) were prepared by radical solution polymerization and sequential IPN technology. Attenuated total reflectance-Fourier transform infrared spectroscopy, swelling properties, mechanical properties, morphology, and glass transition temperature of the films were investigated. FTIR spectra analysis showed that new interaction hydrogen bonds between PVA and PAA were formed. Swelling property of the films in distilled water and different pH buffer solution was studied. Swelling ratio increased with increasing PAA content of IPN films in all media, and swelling ratio decreased with increasing PVA crosslink degree. Tensile strength and elongation at break related not only to the constitution of IPNs but also to the swelling ratio of IPNs.

Identificador

http://ir.ciac.jl.cn/handle/322003/10149

http://www.irgrid.ac.cn/handle/1471x/147295

Idioma(s)

英语

Fonte

Yue YM;Xu K;Liu XG;Chen Q;Sheng X;Wang PX.Preparation and Characterization of Interpenetration Polymer Network Films Based on Poly(vinyl alcohol) and Poly(acrylic acid) for Drug Delivery,JOURNAL OF APPLIED POLYMER SCIENCE,2008,108(6):3836-3842

Palavras-Chave #CONTROLLED-RELEASE #SOLUTE DIFFUSION #IPN HYDROGELS #SEMI-IPN #PH #BEHAVIORS #MEMBRANES #POLY(N-ISOPROPYLACRYLAMIDE) #ADSORPTION #GELS
Tipo

期刊论文