A Facile and Efficient Synthesis of Polyfunctionalized Pyridin-2(1H)-ones from β-Oxo Amides under Vilsmeier Conditions
| Data(s) |
2008
|
|---|---|
| Resumo |
A facile and efficient one-pot synthesis of polysubstituted pyridin-2(1H)-ones from a variety of beta-oxo amides under Vilsmeier conditions is described, and a mechanism involving sequential halogenation, formylation and intramolecular nucleophilic cyclization is proposed |
| Identificador | |
| Idioma(s) |
英语 |
| Fonte |
Xiang DX;Wang KW;Liang YJ;Zhou GY;Dong DW*.A Facile and Efficient Synthesis of Polyfunctionalized Pyridin-2(1H)-ones from β-Oxo Amides under Vilsmeier Conditions,Organic letters,2008,10(2):345-348 |
| Palavras-Chave | #ONE-POT SYNTHESIS #HAACK REACTION #KETENE DITHIOACETALS #PYRIDINE RINGS #CYCLOADDITION #2-PYRIDONE #REAGENTS #CONSTRUCTION #CYCLIZATION #ANNULATION |
| Tipo |
期刊论文 |
