Concise synthesis of novel practical sulfamide-amine alcohols for the enantioselective addition of diethylzinc to aldehydes
Data(s) |
24/12/2004
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Resumo |
Novel sulfamide-amine alcohol ligands were designed using a grafting strategy and synthesized from readily available starting materials via a simple, efficient method. The key features of these ligands for the asymmetric addition of diethylzinc to aldehydes included stability, enhanced effectiveness without using Ti((OPr)-Pr-i)(4), suitability for a variety of aldehydes, the ability to operate at room temperature, and selectability to afford either absolute configuration products with enantiomeric excess up to >99%. |
Identificador | |
Idioma(s) |
英语 |
Fonte |
毛金成;万伯顺;王荣良;吴凡;陆世维.Concise Synthesis of Novel Practical Sulfamide-Amine Alcohols for the Enantioselective Addition of Diethylzinc to Aldehydes,Journal of Organic Chemistry,2004,69():9123-9127 |
Tipo |
期刊论文 |