薯蓣属植物甾体甙元和甾体皂甙对研究

本文介绍了薯蓣植物中所含甾体皂甙和甾体皂甙元的化学研究概括。阐述了该属植物皂甙和甙元的结构特点，简要介绍了提取分离及结构鉴定的新方法，并把从此属植物中分离得到的甾体皂甙和甾体皂甙元的来源，理化常数及13C-NMR的化学位移值以表格形式列出。本文的实验部分是从四川产黄山药根茎的乙醇提取物中分离得到六种甾体皂甙，其中三个为E—试剂正反应成分，用化学方法及IR、FDMS、13CNMR、1HNMR、DEPT等技术鉴定了他们的结构，都是薯蓣皂甙元的皂甙。The chemical study in steroid saponins and sapogenins from Dioscorea family is reviewed. Their stuctures are discussed, and the newer techniques used in their isolation and structural elucidation are briefly introduced. A compilation of the saponins and sapogenins from dioscorea family along with their available physical data, source and 13CNMR chemical shifts is included. The experimental paper is that six steroidal saponins were isolated from rhizomes of Dioscorea panthaica Prain et burkill from Sichuan province. Of these saponins the three are positive to Ehrlich reagent. With the aid of IR, FDMS, and NMR spectrometric analyses, their chemical structures have been elucidated as: 3-O-[α-L-rhamnopyranosyl(1→4)]-[β-D-glucopyranosyl]-diosgenin,3-O-[α-L-rhamnopyranosyl(1→2)]-[β-D-glucopyranosyl]-diosgenin; 3-O-[α-L-rhamnopyranosyl(1→2)]-[β-D-glucopyranosyl]-26-O-[β-D-glucopyranosyl]-diosgenin,3-O-[α-L-rhamnopy-ranosyl(1→2)]-[α-L-rhamnopyranosyl(1→4)]-β-D-glucopyranosyl-26-O-[β-D-glucopyranosyl]-diosgenin,3-O-[α-L-rhamnopyranosyl(1→2)]-[β-D-glucopyranosyl(1→3)]-β-D-glucopyranosyl-26-O-[β-D-glucopyranosyl]-diosgenin