A Cancer Recognition Method Based on DNA Microarray

The accurate cancer classification is of great importance in clinical treatment. Recently, the DNA microarray technology provides a promising approach to the diagnosis and prognosis of cancer types. However, it has no perfect method for the multiclass classification problem. The difficulty lies in the fact that the data are of high dimensionality with small sample size. This paper proposed an automatic classification method of multiclass cancers based on Biomimetic pattern recognition (BPR). To the public GCM data set, the average correct classification rate reaches 80% under the condition that the correct rejection rate is 81%.

National High Technology Research and Development Program of China 2006AA10A213 National Natural Science Foundation of China 60805011 Ph.D. Programs Foundation of Ministry of Education of China 200800191028 Foundation for State Key Laboratory of Pathogen and Biosecurity 200705 This work is supported by the National High Technology Research and Development Program of China (No. 2006AA10A213) National Natural Science Foundation of China (No. 60805011) the Ph.D. Programs Foundation of Ministry of Education of China (No. 200800191028) and the Foundation for State Key Laboratory of Pathogen and Biosecurity (No. 200705).