Complete nucleotide sequence of the S10 genome segment of grass carp reovirus (GCRV)


Autoria(s): Qiu, T; Lu, RH; Zhang, J; Zhu, ZY
Data(s)

2001

Resumo

Hemorrhagic disease, caused by the grass carp reovirus (GCRV), is one of the major diseases of grass carp in China. Little is known about the structure and function of the gene segments of this reovirus. The S10 genome segment of GCRV was cloned and the complete nucleotide sequence is reported here. The S10 is 909 nucleotides long and contains a large open reading frame (ORF) encoding a protein of 276 amino acids with a deduced molecular weight of approximately 29.7 kDa. Comparisons of the deduced amino acid sequence of GCRV S10 with those of other reoviruses revealed no significant homologies. However, GCRV S10 shared a putative zinc-finger sequence and a similar distribution of hydrophilic motifs with the outer capsid proteins encoded by Coho salmon aquareovirus (SCSV) S10, striped bass reovirus (SBRV) S10, and mammalian reovirus (MRV) S4. It was predicted that this segment gene encodes an outer capsid protein.

Identificador

http://ir.ihb.ac.cn/handle/152342/10030

http://www.irgrid.ac.cn/handle/1471x/59528

Fonte

Qiu, T; Lu, RH; Zhang, J; Zhu, ZY.Complete nucleotide sequence of the S10 genome segment of grass carp reovirus (GCRV),DISEASES OF AQUATIC ORGANISMS,2001,44(1):69-74

Palavras-Chave #Fisheries; Veterinary Sciences #grass carp reovirus (GCRV) #S10 genome segment #nucleotide sequence
Tipo

期刊论文