Mitochondrial DNA mutation m.3635G > A may be associated with Leber hereditary optic neuropathy in Chinese

Leber hereditary optic neuropathy (LHON) was the first disease to be linked to the presence of a mitochondrial DNA (mtDNA) mutation. Nowadays over 95% of LHON cases are known to be caused by one of three primary mutations (m.11778G>A, m.14484T>C, and m.34

We thank patients for participating in this study. We are grateful to Ian Logan for commenting on the text of this paper and the members in Yao's laboratory for helpful discussions. This study was supported by the Hundreds-Talent Program and a special sta