Dibenzocyclooctadiene lignans from the fruits of Schisandra wilsoniana and their anti-HIV-1 activities
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2010
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| Resumo |
Three new dibenzocyclooctadiene lignans, wilsonilignans A-C (1-3), together with nine known ones, were isolated from the fruits of Schisandra wilsoniana. The structures of 1-3 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1-3 were also evaluated for their anti-HIV-1 activities and showed bioactivity with EC50 values of 3.26, 6.18, and 2.87g/ml, respectively. This work was supported by grants from the National Basic Research Program of China (973 Program, 2007CB411600), the National Natural Science Foundation of China (30621092) and Bureau of Science and Technology of Yunnan Province. |
| Identificador | |
| Direitos |
Dibenzocyclooctadiene lignans from the fruits of Schisandra wilsoniana and their anti-HIV-1 activities |
| Fonte |
Yang, Guang-Yu; Li, Yin-Ke; Wang, Rui-Rui; Xiao, Wei-Lie; Yang, Liu-Meng; Pu, Jian-Xin; Zheng, Yong-Tang; Sun, Han-Dong.Dibenzocyclooctadiene lignans from the fruits of Schisandra wilsoniana and their anti-HIV-1 activities,12,470-476,Schisandra wilsoniana; fruits; dibenzocyclooctadiene lignans; anti-HIV-1 activity(SCI-E ):This work was supported by grants from the National Basic Research Program of China (973 Program, 2007CB411600), the National Natural Science Foundation of China (30621092) and Bureau of Science and Technology of Yunnan Province. |
| Palavras-Chave | #Plant Sciences; Chemistry, Applied; Chemistry, Medicinal; Pharmacology & Pharmacy #Schisandra wilsoniana #fruits #dibenzocyclooctadiene lignans #anti-HIV-1 activity |
| Tipo |
期刊论文 |
