Synthesis and HIV-1 integrase inhibition activity of some N-arylindoles


Autoria(s): Xu, H; Liu, WQ; Fan, LL; Chen, Y; Yang, LM; Lv, L; Zheng, YT
Data(s)

2008

Resumo

Eight simple N-arylindoles were designed, synthesized and evaluated as human immunodeficiency virus (HIV)-1 integrase inhibitors in vitro for the first time. Among these compounds, 3b, 3e and 3g demonstrated significant anti-HIV-1 integrase activity. Espe

Identificador

http://159.226.149.42:8088/handle/152453/4639

http://www.irgrid.ac.cn/handle/1471x/47952

Direitos

Synthesis and HIV-1 integrase inhibition activity of some N-arylindoles

Fonte

Xu, H; Liu, WQ; Fan, LL; Chen, Y; Yang, LM; Lv, L; Zheng, YT.Synthesis and HIV-1 integrase inhibition activity of some N-arylindoles,56,720-722,(SCI-E ):

Palavras-Chave #Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy
Tipo

期刊论文