Synthesis and biological evaluation of N-acetyl-beta-aryl-1,2-didehydroethylamines as new HIV-1 RT inhibitors in vitro
| Data(s) |
2007
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| Resumo |
A variety of N-acetyl-o-aryl-1,2-didehydroethylamines were synthesized by direct reduction-acetylation of beta-aryl-nitroolefins and assayed as HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the first time. Compound 7a exhibited a TI v |
| Identificador | |
| Direitos |
Synthesis and biological evaluation of N-acetyl-beta-aryl-1,2-didehydroethylamines as new HIV-1 RT inhibitors in vitro |
| Fonte |
Cheng, P; Jiang, ZY; Wang, RR; Zhang, XM; Wang, Q; Zheng, YT; Zhou, J; Chen, JJ.Synthesis and biological evaluation of N-acetyl-beta-aryl-1,2-didehydroethylamines as new HIV-1 RT inhibitors in vitro,17,4476-4480,(SCI-E): |
| Palavras-Chave | #Chemistry, Medicinal; Chemistry, Organic |
| Tipo |
期刊论文 |
