Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities


Autoria(s): Wang, JS; Zheng, YT; Efferth, T; Wang, RR; Shen, YM; Hao, XJ
Data(s)

2005

Resumo

A diprenylated indole, (E)-3-(3-hydroxymethyl-2-butenyl)-7-(3-methyl-2-butenyl)-1H-indole (1), and six known carbazole alkaloids were isolated from the twigs and leaves of Glycosmis montana Pierre (Rutaceae). Their structures were determined on the basis of analysis of spectral evidence including 1D and 2D NMR and MS. The alkaloids (1-3) exhibited weak to moderate take in vitro inhibitory activity against HIV replication in C8166 cells, and they (as well as carbalexine A and B) had cytotoxic activity against the human leukaemia cell line CCRF-CEM. (c) 2005 Elsevier Ltd. All rights reserved.

Identificador

http://159.226.149.42:8088/handle/152453/4547

http://www.irgrid.ac.cn/handle/1471x/47862

Direitos

Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities

Fonte

Wang, JS; Zheng, YT; Efferth, T; Wang, RR; Shen, YM; Hao, XJ.Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities,66,697-701 ,(SCI-E):

Palavras-Chave #Biochemistry & Molecular Biology; Plant Sciences
Tipo

期刊论文