New rotenoids from roots of Mirabilis jalapa


Autoria(s): Wang, YF; Chen, JJ; Yang, Y; Zheng, YT; Tang, SZ; Luo, SD
Data(s)

2002

Resumo

Four new rotenoids named mirabijalone A-D-1) (1-4), together with 9-O-methyl-4-hydroxyboeravinone B (5), boeravinone C (6) and F (7), and 1,2,3,4-tetrahydro-1-methylisoquinoline-7,8-diol (8), were isolated from the roots of Mirabilis jalapa. The structures of these compounds were determined on the basis of their HR-EI-MS, IR, UV, H-1- and C-13-NMR (DEPT). and 2D NMR (HMQC, HMBC, NOESY) data. Among them, 1,2,3,4-tetrahydro-1-methylisoquinoline-7,8-diol (8) showed a 48% inhibition against HIV-1 reverse transcriptase at 210 mug/ml.

Identificador

http://159.226.149.42:8088/handle/152453/4523

http://www.irgrid.ac.cn/handle/1471x/47837

Direitos

New rotenoids from roots of Mirabilis jalapa

Fonte

Wang, YF; Chen, JJ; Yang, Y; Zheng, YT; Tang, SZ; Luo, SD.New rotenoids from roots of Mirabilis jalapa,85,2342-2348,(SCI-E):

Palavras-Chave #Chemistry, Multidisciplinary
Tipo

期刊论文