Melanoma cell growth inhibition by beta gamma-CAT, which is a novel non-lens betagamma-crystallin and trefoil factor complex from frog Bombina maxima skin

In vertebrates, non-lens beta gamma-crystallins are widely expressed in various tissues but their functions are unknown. The molecular mechanisms of trefoil factors, initiators of mucosal healing and being greatly involved in tumorigenesis, have remained

This work was supported by grants from The Chinese National Natural Science Foundation (30630014 and 30570359), and a grant of "Key Research Direction" (KSCX2-YW-R-088) from The Chinese Academy of Sciences to Y. Zhang.