Functional characterization of the human-specific (type II) form of kallikrein 8, a gene involved in learning and memory

Kallikrein 8 (KLK8) is a serine protease functioning in the central nervous system, and essential in many aspects of neuronal activities. Sequence comparison and gene expression analysis among diverse primate species identified a human-specific splice for

We thank Dr Jin-qiu Zhou (Institute of Biochemistry and Cell Biology, SIBS, CAS, China), who kindly provided the High Five cells. We also thank Dr Wei-zhi Ji (Kunming Institute of Zoology, CAS, China), who kindly provided the stem cell cDNA samples. We th