表面增强拉曼光谱术在生命科学及单分子研究中的应用与进展

本文介绍了表面增强拉曼散射的基本原理及其在生命科学研究中的应用；综述了最近十年来利用表面增强拉曼散射进行单分子和活细胞检测的研究进展以及在活体检测中的应用；对表面增强拉曼光谱术在生命科学研究中的独特优势及发展前景进行了介绍。

The principle of surface-enhanced Raman scattering (SERS) and its application in the life science are described. The recent advances in the research of single molecules, living cells and in vivo detection in the past ten years have been summarized. The unique advantages and perspective of SERS in biomedical studies are also presented.