Inter- and intramolecular enantioselective carbolithiation reactions
| Data(s) |
03/02/2014
03/02/2014
01/02/2013
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| Resumo |
In this review we summarize recent developments in inter- and intramolecular enantioselective carbolithiation reactions carried out in the presence of a chiral ligand for lithium, such as (-)-sparteine, to promote facial selection on a C=C bond. This is an attractive approach for the construction of new carbon-carbon bonds in an asymmetric fashion, with the possibility of introducing further functionalization on the molecule by trapping the reactive organolithium intermediates with electrophiles. |
| Identificador |
Beilstein Journal of Organic Chemistry 9 : 313-322 (2013) 1860-5397 http://hdl.handle.net/10810/11329 10.3762/bjoc.9.36 |
| Idioma(s) |
eng |
| Publicador |
Beilstein Institut |
| Relação |
http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-9-36 |
| Direitos |
© 2013 Gómez-SanJuan et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc) info:eu-repo/semantics/openAccess |
| Palavras-Chave | #alkenes #asymmetric synthesis #carbolithiation #carbometallation #enantioselectivity #lithium |
| Tipo |
info:eu-repo/semantics/article |
