Organocatalytic Enantioselective Formal C(sp(2))-H Alkylation
Data(s) |
2015
|
---|---|
Resumo |
An organocatalytic enantioselective formal C(sp(2))-H alkylation is reported. This alkylative desymmetrization of prochiral 2,2-disubstituted cyclopentene-1,3-dione is catalyzed by a bifunctional tertiary aminourea derivative, utilizes air-stable and inexpensive nitroalkanes as the alkylating agents, and delivers synthetically versatile five-membered carbocycles containing an all-carbon quaternary stereogenic center remote from the reaction site in excellent enantioselectivity. |
Formato |
application/pdf |
Identificador |
http://eprints.iisc.ernet.in/51049/1/jou_ame_che_soc_137-1_130_2015.pdf Manna, Madhu Sudan and Mukherjee, Santanu (2015) Organocatalytic Enantioselective Formal C(sp(2))-H Alkylation. In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137 (1). pp. 130-133. |
Publicador |
AMER CHEMICAL SOC |
Relação |
http://dx.doi.org/ 10.1021/ja5117556 http://eprints.iisc.ernet.in/51049/ |
Palavras-Chave | #Organic Chemistry |
Tipo |
Journal Article PeerReviewed |