Total synthesis of the indole alkaloids henrycinol A and B
| Data(s) |
2014
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|---|---|
| Resumo |
The total synthesis of new indole alkaloids henrycinol A and B were accomplished starting from L-tryptophan methyl ester. The key step is a stereochemically flexible Pictet-Spengler reaction governed by the presence or absence of an N-allyl group in the tryptophan precursor. The natural products henrycinol A and B were synthesized in good overall yield in eight and nine steps, respectively. (C) 2014 Elsevier Ltd. All rights reserved. |
| Formato |
application/pdf |
| Identificador |
http://eprints.iisc.ernet.in/49528/1/tet_70-31_4611_2014.pdf Prasad, Kavirayani R and Nidhiry, John Eugene and Sridharan, Makuteswaran (2014) Total synthesis of the indole alkaloids henrycinol A and B. In: TETRAHEDRON, 70 (31). pp. 4611-4616. |
| Publicador |
PERGAMON-ELSEVIER SCIENCE LTD |
| Relação |
http://dx.doi.org/10.1016/j.tet.2014.05.028 http://eprints.iisc.ernet.in/49528/ |
| Palavras-Chave | #Organic Chemistry |
| Tipo |
Journal Article PeerReviewed |
