Remarkable influence of secondary catalyst site on enantioselective desymmetrization of cyclopentenedione
Data(s) |
2014
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Resumo |
An efficient, robust and highly enantioselective catalytic desymmetrization of 2,2-disubstituted cyclopentene-1,3-diones is developed via direct vinylogous nucleophilic addition of deconjugated butenolides. A remarkable influence of the secondary catalyst site on the enantioselectivity points towards an intriguing mechanistic scenario, possibly by triggering a change in catalyst conformation. |
Formato |
application/pdf |
Identificador |
http://eprints.iisc.ernet.in/48922/1/che_sci_5-4_1627_2014.pdf Manna, Madhu Sudan and Mukherjee, Santanu (2014) Remarkable influence of secondary catalyst site on enantioselective desymmetrization of cyclopentenedione. In: CHEMICAL SCIENCE, 5 (4). pp. 1627-1633. |
Publicador |
ROYAL SOC CHEMISTRY |
Relação |
http://dx.doi.org/10.1039/c3sc53102c http://eprints.iisc.ernet.in/48922/ |
Palavras-Chave | #Organic Chemistry |
Tipo |
Journal Article PeerReviewed |