Aptamers as Theranostic Agents: Modifications, Serum Stability and Functionalisation
| Data(s) |
2013
|
|---|---|
| Resumo |
Aptamers, and the selection process known as Systematic Evolution of Ligands by Exponential Enrichment (SELEX) used to generate them, were first described more than twenty years ago. Since then, there have been numerous modifications to the selection procedures. This review discusses the use of modified bases as a means of enhancing serum stability and producing effective therapeutic tools, as well as functionalising these nucleic acids to be used as potential diagnostic agents. |
| Formato |
application/pdf |
| Identificador |
http://eprints.iisc.ernet.in/48225/1/Sen_13-10_13624_2013.pdf Shigdar, Sarah and Macdonald, Joanna and O'Connor, Michael and Wang, Tao and Xiang, Dongxi and Al Shamaileh, Hadi and Qiao, Liang and Wei, Ming and Zhou, Shu-Feng and Zhu, Yimin and Kong, Lingxue and Bhattacharya, Santanu and Li, ChunGuang and Duan, Wei (2013) Aptamers as Theranostic Agents: Modifications, Serum Stability and Functionalisation. In: SENSORS, 13 (10). pp. 13624-13637. |
| Publicador |
MDPI AG |
| Relação |
http://dx.doi.org/10.3390/s131013624 http://eprints.iisc.ernet.in/48225/ |
| Palavras-Chave | #Organic Chemistry |
| Tipo |
Journal Article PeerReviewed |
