Synthetic glutathione peroxidase mimics: effect of nucleophilicity of the aryl thiol cofactor on the antioxidant activity


Autoria(s): Bhabak, Krishna Pada; Bhowmick, Debasish; Mugesh, Govindasamy
Data(s)

01/08/2013

Resumo

Catalytic activity of a series of potent amide- and amine-based organoselenium compounds are studied in the presence of various aromatic thiols having electron donating and electron withdrawing substituents on the phenyl ring. This study suggests that the antioxidant activities of the synthetic GPx mimics can be significantly increased by the incorporation of a suitable electron donating group on the phenyl ring of an aromatic thiol.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/47405/1/Indi_%20Jour_Chem_Sec_A_52A-%288-9%29%201019_2013.pdf

Bhabak, Krishna Pada and Bhowmick, Debasish and Mugesh, Govindasamy (2013) Synthetic glutathione peroxidase mimics: effect of nucleophilicity of the aryl thiol cofactor on the antioxidant activity. In: Indian Journal of Chemistry Sec A: Inorganic,Bio-inorganic, Physical Theoretical and Analytical Chemistry, 52 (8-9). pp. 1019-1025.

Publicador

National Institute of Science Communication and Information Resources

Relação

http://nopr.niscair.res.in/handle/123456789/20368

http://eprints.iisc.ernet.in/47405/

Palavras-Chave #Inorganic & Physical Chemistry
Tipo

Journal Article

PeerReviewed