Enantiospecific total synthesis of indole alkaloids (+)-eburnamonine, (-)-aspidospermidine and (-)-quebrachamine


Autoria(s): Nidhiry, John Eugene; Prasad, Kavirayani R
Data(s)

01/07/2013

Resumo

An enantiospecific total synthesis of indole alkaloids eburnamonine, aspidospermidine and quebrachamine is described from lactic acid. Synthesis of all three alkaloids is accomplished from a single chiral building block. Johnson-Claisen rearrangement of a chiral allyl alcohol is the main feature for the installation of the required quaternary centre.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/46964/1/Tetr_69-26_5525_2013.pdf

Nidhiry, John Eugene and Prasad, Kavirayani R (2013) Enantiospecific total synthesis of indole alkaloids (+)-eburnamonine, (-)-aspidospermidine and (-)-quebrachamine. In: Tetrahedron, 69 (26). pp. 5525-5536.

Publicador

Elsevier Science

Relação

http://dx.doi.org/10.1016/j.tet.2013.04.097

http://eprints.iisc.ernet.in/46964/

Palavras-Chave #Organic Chemistry
Tipo

Journal Article

PeerReviewed