Remarkable photocytotoxicity of curcumin in HeLa cells in visible light and arresting its degradation on oxovanadium(IV) complex formation
| Data(s) |
2012
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|---|---|
| Resumo |
Curcumin (Hcur) as a cellular imaging and PDT agent shows remarkable photocytotoxicity in HeLa cells in visible light of 400-700 nm giving IC50 = 8.2 +/- 0.2 mu M and its degradation is arrested on formation of photocytotoxic dipyridophenazine (dppz) complex VO(cur)(dppz)Cl] (IC50 = 3.3 +/- 0.4 mu M), while both are less toxic in the dark. |
| Formato |
application/pdf application/pdf text/plain |
| Identificador |
http://eprints.iisc.ernet.in/44929/1/chem_comm_48-62_7702-7704_2012.pdf http://eprints.iisc.ernet.in/44929/2/chem_comm_48-62_7702-7705-supp_2012.pdf http://eprints.iisc.ernet.in/44929/3/c2cc33576j.txt Banerjee, Samya and Prasad, Puja and Hussain, Akhtar and Khan, Imran and Kondaiah, Paturu and Chakravarty, Akhil R. (2012) Remarkable photocytotoxicity of curcumin in HeLa cells in visible light and arresting its degradation on oxovanadium(IV) complex formation. In: CHEMICAL COMMUNICATIONS, 48 (62). pp. 7702-7704. |
| Publicador |
ROYAL SOC CHEMISTRY |
| Relação |
http://dx.doi.org/10.1039/c2cc33576j http://eprints.iisc.ernet.in/44929/ |
| Palavras-Chave | #Molecular Reproduction, Development & Genetics (formed by the merger of DBGL and CRBME) #Inorganic & Physical Chemistry |
| Tipo |
Journal Article PeerReviewed |
