NMRof peptides


Autoria(s): Raghothama, S
Data(s)

01/03/2010

Resumo

Developments and applications of NMR spectroscopy especially with biomolecules has taken big strides over the decades. This review gives a brief overview of peptide analysis by NMR as carried out in the author’s laboratory. A brief introduction to peptide biomolecules and NMR useful parameters are discussed in the beginning. This is followed by diagnostics features observed in NMR for identification of secondary structures. It further goes on to show how a three dimensional structure could be obtained by all-important NOE and hydrogen bond information. Use of heteronuclear experiments, which could be done at natural abundance is also highlighted in getting more details of peptide structures.Applications using Solid state NMR at natural abundance in connecting peptide solution and x-ray structures is demonstrated with couple of examples.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/43318/1/NMRof_peptides.pdf

Raghothama, S (2010) NMRof peptides. In: Journal of the Indian Institute of Science, 90 (1). pp. 145-161.

Publicador

The Indian Institute of Science (IISc)

Relação

http://eprints.iisc.ernet.in/43318/

Palavras-Chave #NMR Research Centre (Formerly SIF)
Tipo

Journal Article

PeerReviewed