DNA recognition by the first tail-to-tail linked distamycin-like oligopeptide dimers
Data(s) |
21/08/2001
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Resumo |
Sequence-specific bidentate binding to double-stranded (ds)-DNA by 'tail-to-tail' linked dimeric, distamycin analogues is described; compared to their monomeric analogues, these dimers exhibit greater affinity and longer binding site size and open up a novel avenue in the design of minor groove binders that overcome the phasing problem. |
Formato |
application/pdf |
Identificador |
http://eprints.iisc.ernet.in/39530/1/DNA_recognition_by_the.pdf Bhattacharya, S and Thomas, M (2001) DNA recognition by the first tail-to-tail linked distamycin-like oligopeptide dimers. In: Chemical Communications (16). pp. 1464-1465. |
Publicador |
Royal Society of Chemistry |
Relação |
http://pubs.rsc.org/en/Content/ArticleLanding/2001/CC/b101105g http://eprints.iisc.ernet.in/39530/ |
Palavras-Chave | #Organic Chemistry |
Tipo |
Journal Article PeerReviewed |