devovo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasite
Data(s) |
16/09/1992
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Resumo |
The human malarial parasite, Image , has been found to synthesize heme Image , despite the accumulation of large quantities of polymeric heme derived from the hemoglobin of the red cell host. The parasite δ-aminolevulinate dehydrase level is significantly lower than that of the host and its inhibition by succinylacetone leads to inhibition of parasite protein synthesis and viability. |
Formato |
application/pdf |
Identificador |
http://eprints.iisc.ernet.in/35162/1/-D-_E_NOVO_BIOSYNTHESIS_OF_HEM.pdf Surolia, Namita and Padmanaban, Govindarajan (1992) devovo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasite. In: Biochemical and Biophysical Research Communications, 187 (2). pp. 744-750. |
Publicador |
Elsevier science |
Relação |
http://dx.doi.org/10.1016/0006-291X(92)91258-R http://eprints.iisc.ernet.in/35162/ |
Palavras-Chave | #Biochemistry #Others |
Tipo |
Journal Article PeerReviewed |