Conformations of peptides containing Z-alpha,beta-dehydroleucine (delta ZLeu). A comparison of Boc-Pro-delta ZLeu-Gly-NHEt and Boc-Pro-delta ZPhe-Gly-NHEt.


Autoria(s): Uma, K; Balaram, P; Kaur, Paramjeet; Kumar Sharma, Ashwani; Chauhan, VS
Data(s)

01/06/1989

Resumo

Two tripeptides of the type Boc-Pro-ΔZX-Gly-NHEt (where X = Leu, Phe) have been synthesized and their solution conformations investigated by 270 MHz 1H n.m.r. and i.r. spectroscopy. These conformational studies indicated that ΔZLeu, similar to ΔZPhe, has a strong tendency to stabilize folded Type II β-turn conformations when present at i + 2 position.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/31368/1/confor.pdf

Uma, K and Balaram, P and Kaur, Paramjeet and Kumar Sharma, Ashwani and Chauhan, VS (1989) Conformations of peptides containing Z-alpha,beta-dehydroleucine (delta ZLeu). A comparison of Boc-Pro-delta ZLeu-Gly-NHEt and Boc-Pro-delta ZPhe-Gly-NHEt. In: International Journal of Biological Macromolecules, 11 (3). pp. 169-171.

Publicador

Elsevier Science

Relação

http://dx.doi.org/10.1016/0141-8130(89)90063-9

http://eprints.iisc.ernet.in/31368/

Palavras-Chave #Molecular Biophysics Unit
Tipo

Journal Article

PeerReviewed