Mechanism of hydroxylation of aromatic compounds: II. Evidence for the involvement of superoxide anions in enzymatic hydroxylations
| Data(s) |
18/12/1972
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|---|---|
| Resumo |
The mechanism of hydroxylation reactions catalyzed by m-hydroxybenzoate-4-hydroxylase and anthranilate hydroxylase from Aspergillus niger was investigated using superoxide dismutase from ovine erythrocytes. Inclusion of superoxide dismutase in the assay mixtures of the two enzymes resulted in complete inhibition of the hydroxylation reaction, indicating the possible involvement of superoxide anions (O2−) in these reactions. |
| Formato |
application/pdf |
| Identificador |
http://eprints.iisc.ernet.in/28603/1/Hyd.pdf Kumar, Prema R and Ravindranath, SD and Vaidyanathan, CS and Rao, Appaji N (1972) Mechanism of hydroxylation of aromatic compounds: II. Evidence for the involvement of superoxide anions in enzymatic hydroxylations. In: Biochemical and Biophysical Research Communications, 49 (6). pp. 1422-1426. |
| Publicador |
Elsevier Science |
| Relação |
http://dx.doi.org/10.1016/0006-291X(72)90497-4 http://eprints.iisc.ernet.in/28603/ |
| Palavras-Chave | #Biochemistry |
| Tipo |
Journal Article PeerReviewed |
