Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication
| Contribuinte(s) |
University of Helsinki, Institute for Molecular Medicine Finland (FIMM) University of Helsinki, Neurokirurgian yksikkö University of Helsinki, Institute for Molecular Medicine Finland (FIMM) University of Helsinki, Institute for Molecular Medicine Finland (FIMM) University of Helsinki, Institute for Molecular Medicine Finland (FIMM) |
|---|---|
| Data(s) |
2010
|
| Resumo |
Neuroblastoma has successfully served as a model system for the identification of neuroectoderm-derived oncogenes. However, in spite of various efforts, only a few clinically useful prognostic markers have been found. Here, we present a framework, which integrates DNA, RNA and tissue data to identify and prioritize genetic events that represent clinically relevant new therapeutic targets and prognostic biomarkers for neuroblastoma. |
| Formato |
13 |
| Identificador |
http://hdl.handle.net/10138/23854 1471-2407 |
| Idioma(s) |
eng |
| Publicador |
BIOMED CENTRAL LTD |
| Relação |
BMC Cancer |
| Fonte |
Wolf , M , Korja , M , Karhu , R , Edgren , H , Kilpinen , S , Ojala , K , Mousses , S , Kallioniemi , A & Haapasalo , H 2010 , ' Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication ' BMC Cancer , vol 10 , no. 181 , pp. - . , 10.1186/1471-2407-10-181 |
| Palavras-Chave | #COMPARATIVE GENOMIC HYBRIDIZATION #IN-SITU HYBRIDIZATION #MYCN-AMPLIFICATION #COPY NUMBER #SMAC/DIABLO EXPRESSION #OVEREXPRESSED GENES #CERVICAL-CANCER #DOWN-REGULATION #DNA #IDENTIFICATION #318 Medical biotechnology |
| Tipo |
A1 Refereed journal article info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
